130. Purification of Large Scale mRNA Encoding ZFN Nucleases by dHPLC Technology
نویسندگان
چکیده
منابع مشابه
Expanded activity of dimer nucleases by combining ZFN and TALEN for genome editing
Our ability to precisely and efficiently edit mammalian and plant genomes has been significantly improved in recent years, partially due to increasing use of designer nucleases that recognize a pre-determined DNA sequence, make a specific DNA double-strand break, and stimulate gene targeting. A pair of zinc finger nucleases (ZFNs) or transcription activator-like effector nucleases (TALENs) that...
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ژورنال
عنوان ژورنال: Molecular Therapy
سال: 2016
ISSN: 1525-0016
DOI: 10.1016/s1525-0016(16)32939-2